All user data (site manager, recent connections, transfer queue) is stored in %APPDATA%\FileZilla\ as XML files (sitemanager.xml, filezilla.xml), not the registry.
On 64-bit Windows the installer places a 64-bit binary; the registry path is HKLM\SOFTWARE\FileZilla Client without WOW6432Node.
FileZilla does not store passwords in the registry; credentials in sitemanager.xml are obfuscated but not encrypted — treat that file as sensitive.
The portable version of FileZilla does not create any registry entries.